Weekly Exenatide Therapy

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منابع مشابه

Exenatide once weekly in type 2 diabetes.

The difficulties of maintaining long-term glycaemic control with available antidiabetic treatments in patients with type 2 diabetes have led to the need for additional treatments that can replace or be safely combined with existing agents. Patients with type 2 diabetes who have not achieved adequate glucose control at the maximum tolerated doses of their oral therapies have had no alternative o...

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Exenatide once weekly: clinical outcomes and patient satisfaction

BACKGROUND Type 2 diabetes mellitus (T2DM) is a complex disorder in which interactions between environmental and genetic factors result in the development of insulin resistance (in most cases) and progressive pancreatic β-cell failure. The currently available oral anti-diabetes treatments are effective as monotherapy; however, due to the progressive decline in β-cell function, most patients wil...

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Exenatide Once Weekly for Smoking Cessation: A Randomized Clinical Trial

Background: Cigarette smoking is the greatest preventable cause of morbidity and premature mortality in the US. Approved pharmacological treatments for smoking cessation are only marginally effective, underscoring the need for improved pharmacotherapies. Glucagon-like peptide-1 (GLP-1) is produced in the intestinal L-cells and in the hindbrain nucleus solitarius. GLP-1 functions to maintain glu...

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Once-Weekly Exenatide Versus Once- or Twice-Daily Insulin Detemir

OBJECTIVE This multicenter, open-label, parallel-arm study compared the efficacy and safety of exenatide once weekly (EQW) with titrated insulin detemir in patients with type 2 diabetes inadequately controlled with metformin (with or without sulfonylureas). RESEARCH DESIGN AND METHODS Patients were randomized to EQW (2 mg) or detemir (once or twice daily, titrated to achieve fasting plasma gl...

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Efficacy and safety of exenatide once‐weekly vs exenatide twice‐daily in Asian patients with type 2 diabetes mellitus

AIMS/INTRODUCTION To compare safety and efficacy of the extended-release formulation exenatide once weekly (EQW) vs exenatide twice daily (EBID) for 26 weeks in type 2 diabetes patients from China, India, Japan, South Korea and Taiwan. MATERIALS AND METHODS A randomized, comparator-controlled, open-label study included 681 patients with type 2 diabetes inadequately controlled (hemoglobin A1c ...

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ژورنال

عنوان ژورنال: Journal of Pharmacy Technology

سال: 2014

ISSN: 8755-1225,1549-4810

DOI: 10.1177/8755122513518189